Moving too quickly to give people Covid booster jabs would deprive scientists of data on how well the vaccines work, AstraZeneca bosses have said.
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"We do not yet know whether that third dose is clinically needed," they say in the Telegraph.
It has already been announced that half a million of the most vulnerable in the UK will be offered a third dose.
But a separate booster programme, planned for September, has yet to be confirmed.
Health Secretary Sajid Javid said, on Wednesday, he was "confident" a booster programme could begin this month but was awaiting advice on who should be eligible.
In their article, AstraZeneca chief-executive Pascal Soriot and biopharmaceuticals-research-and-development executive-vice-president Sir Mene Pangalos say giving the most vulnerable, who may not have built up a full immune response from the first two, a third, top-up dose is "sensible".
But any decision to give a third, booster jab "to large swathes of the population", to extend their protection from the first two, must be based on clinical data, which is only a few weeks away from being published.